The Dangers of Oral Non-Bioidentical Estrogen: Why Bioidentical Hormones Are Safer for Women's Health
by Dr. Beth Meneley, DAOM, L.Ac.
When considering hormone replacement therapy (HRT) for menopause and perimenopause, it’s essential to understand the risks and benefits of different treatments. Traditional oral non-bioidentical estrogen is commonly prescribed, but it poses serious health risks, including blood clots and increased cancer risks. At Evolved Menopause, we advocate for bioidentical hormone replacement therapy (BHRT), which is a safer and more natural alternative to support long-term health.
The Risks of Oral Non-Bioidentical Estrogen
Oral non-bioidentical estrogen can negatively impact cardiovascular health by increasing the risk of blood clots, heart attack, and stroke. This happens because, when taken orally, estrogen must pass through the liver first, triggering the production of clotting factors. Studies have shown that oral non-bioidentical estrogen significantly raises these risks compared to other forms of hormone delivery.
Additionally, non-bioidentical estrogen often breaks down through unhealthy metabolic pathways in the body. Instead of metabolizing through the safer 2-OH pathway, which promotes proper estrogen elimination, it can lead to the 4-OH pathway, which is associated with DNA damage and a heightened risk of cancers, including breast cancer.
Why Bioidentical Estrogen Is the Better Choice
Unlike synthetic or non-bioidentical hormones, bioidentical estrogen is molecularly identical to the estrogen your body naturally produces. This makes it easier for your body to metabolize safely. With bioidentical estrogen, especially when delivered transdermally through a patch or gel, the risks of blood clotting, heart issues, and cancer are significantly lower.
Bioidentical hormones also promote a healthier metabolic process. They are more likely to follow the safer 2-OH pathway, reducing the risk of estrogen-related cancers. The overall balance that bioidentical estrogen provides helps regulate your body naturally, without the dangerous side effects often seen with non-bioidentical treatments.
Why Bioidentical Progesterone is Essential
When using any form of estrogen therapy, it’s critical to include bioidentical progesterone. Progesterone balances estrogen’s effects, especially on the uterine lining, helping prevent the risk of endometrial cancer. It also supports mood, sleep, and hormonal balance, ensuring a well-rounded approach to hormone replacement therapy.
The Hidden Risks of Non-Bioidentical Estrogen Patches
Even non-bioidentical estrogen patches carry significant risks. Although transdermal delivery bypasses the liver and reduces the risk of blood clots, synthetic forms of estrogen used in these patches can still increase inflammation and disrupt metabolic processes. Only bioidentical hormone patches are recommended to safely restore balance without unnecessary health risks.
Supporting Your Body with Detox and Gut Health
At Evolved Menopause, we believe that liver detox and gut health play a crucial role in hormone metabolism. Your liver is responsible for breaking down and detoxifying hormones, ensuring they are processed through the correct metabolic pathways. A healthy liver supports the 2-OH pathway, preventing estrogen from metabolizing into harmful forms.
Incorporating liver detox supplements like DIM (Diindolylmethane), milk thistle, and glutathione can promote healthy estrogen breakdown. At the same time, maintaining a healthy gut is essential. Your gut helps eliminate excess estrogen from the body, preventing it from being reabsorbed and leading to hormonal imbalances. Incorporating probiotics, fiber, and a nutrient-dense diet can optimize hormone elimination and balance.
The Bottom Line: Choose Bioidentical Hormones for Optimal Health
When it comes to hormone replacement therapy, choosing bioidentical hormones is not only safer but also more effective. By avoiding oral non-bioidentical estrogen, you can reduce the risks of blood clots, heart disease, and breast cancer. At Evolved Menopause, we offer a holistic approach to hormone balance, combining bioidentical hormone therapy with liver and gut health optimization to ensure your hormones work harmoniously within your body.
If you're ready to embrace a new phase of wellness, explore the benefits of bioidentical hormone therapy with our expert team at Evolved Menopause. We’re here to help you thrive with safer, smarter hormone solutions.
